0.1µm AseptiCap KS 5″, 10″, 20″, 30″



AseptiCap KS PES membrane large capsule filters are validated for mycoplasma removal and are used for sterile media filtration in mammalin cell culture.

Special features

Consistent and Reliable Quality: AseptiCap capsule filters are produced with ISO 9001 certified quality management systems
Regulatory Compliance: Meet all pharmacopeial and compendia requirements and are registered with USFDA DMF #015554
Low Protein Binding: Results in increased overall product yield
High Throughputs: Translates to lower filtration costs, less number of filter changes and overall economy of operations
Low Extractables: Mean less addition to impurity profile of the biological product from the filters


    Sterile Filtration of:

  • Cell culture media
  • Cell culture media containing serum
  • Media additives
  • Final product concentrates


Membrane 0.1 μm Hydrophilic PES
Prefilter Membrane 0.2 μm or 0.45 μm Hydrophilic PES
Support Layers Polyester
Plastic parts Polypropylene
Integrity Testing / Retention
Bubble Point > 31psi with 50% IPA/water solution
Max. Air Diffusion Flow (@ 50psi (3.51 Kg/cm²) with water)
< 15 ml/min < 29 ml/min < 58 ml/min < 87 ml/min
Bacterial Retention LRV > 7 for Acholeplasma laidlawii ATCC 23206 per cm² of filter area
5″ 10″ 20″ 30″
Effective Filtration Area (Nominal)
3000cm² 6000cm² 12000cm² 18000cm²
Dimension (End to End) – 1½” Sanitary Flange Inlet ½” Hose Barb Outlet
212 mm 334 mm 620 mm 870 mm
Dimension (End to End) – ¾” Sanitary Flange I/O
214 mm 335 mm
Dimensions (End to End) Inline Capsule Filters – 1½” Sanitary Flange I/O
205 mm 330 mm 600 mm 855 mm
Dimensions (End to End) Inline Capsule Filters – ½” Single Step Hose Barb I/O
218 mm 336 mm 630 mm 890 mm
Clean Water Flow Rate @ 10 psi with 1½” Sanitary Flange connection
8 lpm 17 lpm 29 lpm 45 lpm
Dimension (End to End) – 1″ Hose Barb I/O
405 mm 635 mm 895 mm
Operational Radius (with Vent/ Drain)
78 mm 78 mm 78 mm 78 mm
Dimension (End to End) – 3/8″ Hose Barb I/O
211 mm 332 mm 634 mm 885 mm
Vent and Drain ¼” Hose Barb with Silicone “O” rings
Max. Operating Temperature 80 °C @ < 30 psi (2 Kg/cm²)
Max. Differential Pressure 60 psi (4 Kg/cm²) @ 30 °C
pH Compatibility Compatible with pH range of 1-10
Sterilization By Gas Sterilizable by Ethylene Oxide
Sterilization By Autoclave Autoclavable at 125°C for 30 minutes, 25 cycles and it cannot be in-line steam sterilized
Shelf Life 3 years after EO sterilization
Toxicity Passes Bioreactivity test, In Vivo, as per USP <88> for Class VI plastics
Cytotoxicity Passes Biological Reactivity Tests, In Vitro, USP <87> for cytotoxicity
Bacterial Endotoxin Aqueous extracts exhibit < 0.25 EU/ml as established by Limulus Amebocyte Lysate (LAL) Test
Bioburden Bioburden level is < 1000 cfu/filter device as per ISO 11737-1 : 2018
Non Fiber Releasing Passes test as per USP and comply with USFDA 21 CFR Part 210.3(b)(6) for fiber release
TOC and Conductivity Meets the WFI requirements of USP for TOC <643> and Conductivity <645> after a 10 liter flush for 5” capsule filters and 20 liter flush for 10” capsule filters
Particle Release Passes USP test for particulates in injectables
Indirect Food Additive All Polypropylene components meet the FDA Indirect Food Additive requirements cited in 21 CFR 177.1520
Extractables with WFI Passes NVR test as per USP <661>
Oxidizable Substances Within limits as specified in USP <1231>
Particle Shedding Passes USP test for particulates in injectables.
Quality Management System ISO-9001 Certified
USFDA DMF No. 015554

Ordering Information

AseptiCap KS (0.2 μm Upstream) LKS1
AseptiCap KS (0.45 μm Upstream) LKSX
Size Code
5″ 53
10″ 54
20″ 55
30″ 56
Pore Size
Pore Size Code
0.1µm 36
I/O Connection
Connection Code
1½” Sanitary Flange E
3/4” Sanitary Flange** S
3/8” Hose Barb I
Single Step ½”Hose Barb Q
1” Hose Barb Z
Inline X
T-line* T
Non Sterile 1
EO Sterile 2
Pack Size
Pack Size Code
1 01

*T-line is not available in 5″ Capsule filter
*T-line Capsule filter are available with 1½” Sanitary Flange I/O connection only
**3/4″ Sanitary Flange end connection is available only in 5″ and 10″ capsule filters

LKSX 54 36 EE X X 1 01

Example for Non Sterile: LKSX5436EEXX101 Example for EO Sterile: LKSX5436EEXX201

Flow rate