0.1µm AseptiCap KS-γ 1″, 2″, 5″, 8″



AseptiCap KS-γ PES membrane capsule filters are validated for mycoplasma removal and are used for sterile media filtration in mammalian cell culture.

These are gamma sterilizable and are available in a wide range of sizes and end connections.

Special features

Consistent and Reliable Quality: AseptiCap capsule filters are produced with ISO 9001 certified quality management systems
Regulatory Compliance: Meet all pharmacopeial and compendia requirements and are registered with USFDA DMF #015554
Low Protein Binding: Results in increased overall product yield
High Throughputs: Translates to lower filtration costs, less number of filter changes and overall economy of operations
Low Extractables: Mean less addition to impurity profile of the biological product from the filters


Sterile Filtration of:

  • Cell culture media
  •  Cell culture media containing serum
  •  Media additives
  •  Final product concentrates


Membrane 0.1 μm Hydrophilic PES
Upstream Membrane 0.2 µm or 0.45 µm Hydrophilic PES
Support Layers Polyester
Plastic parts Gamma Stable Polypropylene
Integrity Testing / Retention
Bubble Point > 31psi with 50% IPA/Water solution
Bacterial Retention LRV > 7 for Acholeplasma laidlawii ATCC 23206 per cm² of filter area
1″ 2″ 5″ 8″
Effective Filtration Area (Nominal)
250cm² 500cm² 1000cm² 2000cm²
Dimensions (End to End) – 1½” Sanitary Flange I/O
92 mm 112 mm 164 mm 216 mm
Dimension (End to End) – ½” Hose Barb I/O
90 mm 112 mm 162 mm 214 mm
Dimension (End to End) – 1½” Sanitary Flange Inlet ½” Single Step Hose Barb Outlet
112 mm 165 mm 216 mm
Dimensions (End to End) – ¾” Sanitary Flange I/O
85 mm 104 mm 155 mm 206 mm
Dimension (End to End) – ½” Single Step Hose Barb I/O
115 mm 162 mm 218 mm
Clean water Flow Rate @ 10 psi with ½” Hose Barb Connection
1.3 lpm 2.5 lpm 4.8 lpm 6.5 lpm
Operational Radius (with Vent/ Drain)
30 mm 65 mm 65 mm 65 mm
Vent and Drain
¼” Hose Barb with Silicone “O” rings for 2″, 5″ and 8″ only
Max. Operating Temperature 80 °C @ < 30 psi (2 Kg/cm²)
Max. Differential Pressure 60 psi (4 Kg/cm²) @ 30 °C
Sterilization By Irradiation Gamma Irradiatiable up to 50 kGy. These filters should not be autoclaved or in-line steam sterilized.
Shelf Life 2 years after gamma sterilization
Toxicity Passes Bioreactivity test, In Vivo, as per USP <88> for Class VI plastics
Cytotoxicity Passes Biological Reactivity Tests, In Vitro, USP <87> for cytotoxicity
Bacterial Endotoxin Aqueous extracts exhibit < 0.25 EU/ml as established by Limulus Amebocyte Lysate (LAL) Test
Bioburden Bioburden level is < 1000 cfu/filter device as per ISO 11737-1 : 2018
Non Fiber Releasing Passes test as per USP and comply with USFDA 21 CFR Part 210.3(b)(6) for fiber release
TOC and Conductivity Meets the WFI requirements of USP for TOC <643> and Conductivity <645> after a 3 liter flush
Particle Release Passes USP test for particulates in injections
Indirect Food Additive Comply with USFDA 21 CFR Part 177.1520
Extractables with WFI Passes NVR test as per USP <661>
Oxidizable Substances Within limits as specified in USP <1231>
Particle Shedding Passes USP test for particulates in injectables
Quality Management System ISO-9001 Certified
USFDA DMF No. 015554
pH Compatibility Compatible with pH range of 1 – 10

Ordering Information

AseptiCap KS-γ (0.2 µm Upstream) DKS1
AseptiCap KS-γ (0.45µm Upstream) DKSX
Size Code
1″ 51
2″ 52
5″ 53
8″ 57
Pore Size
Pore Size Code
0.1µm 36
I/O Connection
Connection Code
¼” SHB A
½” MNPT* C
½” Hose Barb D
1½” Sanitary Flange E
¾” Sanitary Flange S
Quick Connector J
Single Step ½” Hose Barb* Q
Female Luer Lock U
Male Luer Slip** W
3/8″ Hose Barb* I
3/16″ Hose Barb*** N
Radiation Sterilizable
Yes R
No**** X
Yes***** B
No Bell X
Bell with cover***** C
Non Sterile 1
Gamma Sterile 3
Pack Size
Pack Size Code
1 01

*1” Capsule Filters are not available with ½” Single step Hose Barb, ½” MNPT and 3/8″ Hose Barb
** Male luer slip is available only in 1” capsule filter as outlet
*** 3/16″ Hose Barb end connection is available in:

  • 1″ and 2″ capsule filters as inlet and outlet
  • 5″ capsule filters as outlet only

**** Gamma sterilized filters cannot be gamma irradiated again
***** Bell and bell with cover is available with:

  • ½” HB outlet connections in 1″, 2″, 5″ and 8″ capsule filters
  • ¼” SHB outlet connection in 1″ capsule filters only


DKSX 57 36 DD R X 1 01

Example for Non Sterile: DKSX5136EERX101 Example for gamma Sterile: DKSX5136EEXX301

Flow rate